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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Tumor-associated calcium signal transducer 2 ： ウィキペディア英語版 TACSTD2 Tumor-associated calcium signal transducer 2 is a protein that in humans is encoded by the ''TACSTD2'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4070 )〕 This intronless gene encodes a carcinoma-associated antigen defined by the monoclonal antibody GA733. This antigen is a member of a family including at least two type I membrane proteins. It transduces an intracellular calcium signal and acts as a cell surface receptor. Mutations of this gene result in gelatinous drop-like corneal dystrophy, an autosomal recessive disorder characterized by severe corneal amyloidosis leading to blindness.〔 This antigen is the target of the antibody-drug conjugate Sacituzumab govitecan. ==References== 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「TACSTD2」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.